An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Concept Breadcrumbs

Preferred Term:

CCR1 receptor

Chemokine (C-C Motif) Receptor 1, encoded by the CCR1 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells (monocytes, macrophages, neutrophils and eosinophils) to the site of inflammation. This gene may have roles in host protection from inflammatory response, and susceptibility to virus and parasite.
Concept Schemes:
Broader Concept:
Entry Terms:
  • C-C chemokine receptor type 1
  • chemokine (C-C motif) receptor 1
  • LD78 cytokine receptor
  • RANTES receptor
  • C-C CKR1 receptor
  • macrophage inflammatory protein 1alpha receptor
  • CD191 antigen
Download this Concept:
RDF/XMLCreated 2015-03-10, last modified 2015-11-16