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NAL Agricultural Thesaurus
U.S. Department of Agriculture
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Concept Breadcrumbs

Research, Technology, Methods > research > animal research > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > immunologic receptors > cytokine receptors > chemokine receptors > CCR1 receptor
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > immunologic receptors > cytokine receptors > chemokine receptors > CCR1 receptor
Research, Technology, Methods > research > animal research > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > immunologic receptors > cytokine receptors > chemokine receptors > CCR1 receptor
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > immunologic receptors > cytokine receptors > chemokine receptors > CCR1 receptor
Research, Technology, Methods > research > animal research > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > G-protein coupled receptors > chemokine receptors > CCR1 receptor
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > G-protein coupled receptors > chemokine receptors > CCR1 receptor
Research, Technology, Methods > research > animal research > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > G-protein coupled receptors > chemokine receptors > CCR1 receptor
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > G-protein coupled receptors > chemokine receptors > CCR1 receptor
Preferred Term:

receptor CCR1

Definition:
Receptor 1 de quimiocina C-C, codificado por el gen CCR1. Es un miembro de la familia de receptores de quimiocina beta y una proteína transmembranal de siete hélices, similar a los receptores acoplados a proteínas G. Entre los ligandos de este receptor se incluyen la proteína inflamatoria de macrófagos 1 alfa (MIP-1 alfa), la proteína expresada y secretada por células T normales reguladas tras la activación (RANTES), la proteína 3 quimioatrayente de monocitos (MCP-3) y el factor 1 inhibidor del progenitor mieloide (MPIF-1). La transducción de señales mediada de las quimiocinas y sus receptores resulta esencial para atraer células efectoras inmunitarias (monocitos, macrófagos, neutrófilos y eosinófilos) al lugar de la inflamación. Este gen puede realizar funciones en la protección del huésped de una respuesta inflamatoria y en la susceptibilidad a virus y parásitos.
Concept Schemes:
https://lod.nal.usda.gov/nalt
Términos Genéricos:
receptores de quimiocinas
Términos Relacionados:
URI:
https://lod.nal.usda.gov/nalt/243409
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RDF/XMLCreated 2015-03-10, last modified 2015-11-16