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advanced glycation end products

Products derived from the nonenzymatic reaction of glucose and proteins in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of diabetes mellitus.
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Entry Terms:
  • advanced glycation end product
  • advanced glycation end-products
  • advanced glycosylation end products
  • advanced glycation endproducts
  • advanced glycated end products
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RDF/XMLCreated 2014-08-29, last modified 2014-11-17