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Preferred Term:

wnt proteins

Definition:
Wnt proteins are a large family of secreted glycoproteins that play essential roles in embryonic and fetal development, and tissue maintenance. They bind to frizzled receptors and act as paracrine protein factors to initiate a variety of signal transduction pathways. The canonical wnt signaling pathway stabilizes the transcriptional coactivator beta catenin.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • wnt factors
  • wingless type proteins
URI:
https://lod.nal.usda.gov/nalt/341523
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RDF/XMLCreated 2020-07-20, last modified 2020-10-29