Preferred Term:
aldo-keto reductases
Definition:
A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, ketosteroids; keto-prostaglandins, and quinones. they are monomers of approximately 37 kda and are characterized by a parallel beta-8 (beta sheet)-alpha 8 (alpha helices)-barrel structure that contains the nadp binding site. This conformation favors aromatic and apolar substrates.
Concept Schemes:
NALT Full
Broader Concept:
Narrower Concepts:
URI:
https://lod.nal.usda.gov/nalt/341300
Download this Concept:
RDF/XMLCreated 2020-07-09, last modified 2020-10-29