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Preferred Term:

fibrillins

Definition:
A family of extracellular matrix glycoproteins that is structurally similar to latent TGF-beta binding proteins, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm microfibrils that function in a variety of cell interactions with the extracellular matrix and developmental processes such as elastic tissue maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
Concept Schemes:
NALT Full
URI:
https://lod.nal.usda.gov/nalt/317258
Download this Concept:
RDF/XMLCreated 2018-05-25, last modified 2018-11-14