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CXCR4 receptor
Definition:
CXCR4 shares features common to G protein coupled receptors. CXCR4 is a receptor for the CXC chemokine PBSF/SDF1 and functions as a co-receptor for HIV-1. CXCR4 is broadly expressed in the immune and the central nervous systems and can mediate migration of resting leukocytes and hematopoietic progenitors in response to SDF1. PBSF/SDF1 and CXCR4 define a signaling system for organ vascularization.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- neuropeptide Y receptor Y3
- chemokine (C-X-C motif) receptor 4
- LESTR (leukocyte-derived seven transmembrane domain receptor)
- LPS-associated protein 3
- fusin
- CD184 antigen
- lipopolysaccharide-associated protein 3
- SDF-1 (stromal cell-derived factor 1 receptor)
- chemokine (C-X-C) receptor 4
- seven-transmembrane-segment receptor, spleen
- LAP-3 protein
- C-X-C chemokine receptor type 4
- SDF1-PBSF receptor
- PSSF receptor (pre-B cell growth-stimulating factor receptor)
- CXC chemokine receptor 4
- SDF-1 receptor
- LESTR receptor
URI:
https://lod.nal.usda.gov/nalt/243588
Download this Concept:
RDF/XMLCreated 2015-03-10, last modified 2015-11-16