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Preferred Term:

CCR8 receptor

Definition:
This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • CDw198 antigen
  • chemokine receptor CLR-L1
  • CC-CKR8 receptor
  • chemokine receptor CKRL1
  • CKR8 receptor
  • chemokine receptor TER1
  • chemokine (C-C) receptor 8
  • C-C chemokine receptor type 8
  • GPR-CY6 (G-protein coupled receptor-CY6)
  • chemokine (C-C motif) receptor 8
  • CC chemokine receptor 8
URI:
https://lod.nal.usda.gov/nalt/243493
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RDF/XMLCreated 2015-03-10, last modified 2015-11-16