Preferred Term:
cell cycle checkpoints
Definition:
Regulatory signaling systems that control the progression through the cell cycle. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the genome and cytoplasm, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- cell cycle arrest
URI:
https://lod.nal.usda.gov/nalt/232248
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RDF/XMLCreated 2014-10-10, last modified 2018-05-09