Preferred Term:
fibroblast growth factor receptor 2
Definition:
A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the mesenchyme and is activated by fibroblast growth factor 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in epithelial cells and is activated by fibroblast growth factor 7 and fibroblast growth factor 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., Apert syndrome; and Crouzon syndrome).
Concept Schemes:
NALT Full
Broader Concept:
Narrower Concepts:
Entry Terms:
- BEK protein tyrosine kinase
- FGFR2 receptor
- Bek fgf receptor kinase
- BEK fibroblast growth factor receptor
- fibroblast growth factor receptor 2c
- FGFR2 protein
- FGFR-2 (fibroblast growth factor receptor 2)
- FGFR2c
- FGFR-2 receptor
- fibroblast growth factor receptor 2b
- fibroblast growth factor receptor-2
- fibroblast growth factor receptor type 2
- FGFR-2 protein
- BEK fibroblast growth factor receptor kinase
- FGFR2b
URI:
https://lod.nal.usda.gov/nalt/222865
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RDF/XMLCreated 2014-07-25, last modified 2015-03-26