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angiopoietin-2
Definition:
An angiopoietin that is closely related to angiopoietin-1. It binds to the TIE-2 receptor without receptor stimulation and antagonizes the effect of angiopoietin-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of blood vessel branching and sprouting.
Concept Schemes:
NALT Full
Broader Concept:
URI:
https://lod.nal.usda.gov/nalt/215208
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RDF/XMLCreated 2014-04-22, last modified 2014-11-17