Preferred Term:
tumor suppressor genes
Definition:
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- metastasis suppressor genes
- cancer suppressor genes
- tumour suppressor genes
- antioncogenes
- anti-oncogenes
- tumour suppressing genes
- tumor suppressing genes
URI:
https://lod.nal.usda.gov/nalt/207970
Download this Concept:
RDF/XMLCreated 2013-11-13, last modified 2014-02-18
Closely Matching Concepts: