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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > lipoprotein receptors > low density lipoprotein receptors
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > receptors > lipoprotein receptors > low density lipoprotein receptors
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > lipoprotein receptors > low density lipoprotein receptors
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > lipoprotein receptors > low density lipoprotein receptors
Preferred Term:

receptores de lipoproteínas de baja densidad

Definition:
Receptores que se hallan en la membrana plasmática de las células no hepáticas y que se unen específicamente al colesterol LDL. Se localizan en regiones especializadas denominadas vesículas recubiertas. La hipercolesterolemia es causada por un defecto genético alélico que puede ser de tres tipos: 1) receptores que no se unen a las LDL, 2) receptores con unión reducida a las LDL y 3) receptores que se unen normalmente, pero sin internalización de las LDL. Por lo tanto, la entrada del colesterol en la célula se ve afectada y el colesterol no produce la retroalimentación intracelular en la 3-hidroxi-3-metilglutaril-CoA reductasa.
Concept Schemes:
https://lod.nal.usda.gov/nalt
Términos Genéricos:
receptores de lipoproteínas
URI:
https://lod.nal.usda.gov/nalt/322237
Download this Concept:
RDF/XMLCreated 2018-07-11, last modified 2018-11-14