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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > binding proteins > transport proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > binding proteins > transport proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > transport proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > membrane proteins > transport proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > peptides > intracellular signaling peptides and proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > peptides > intracellular signaling peptides and proteins > signal transducing adaptor proteins > insulin receptor substrate proteins
Preferred Term:

proteínas del sustrato receptor de insulina

Definition:
Grupo de proteínas de señalización estructuralmente relacionadas, fosforiladas por la proteína tirosina quinasa receptora de insulina. Comparten un dominio N-terminal homólogo a la pleckstrina, que es un dominio de unión a la fosfotirosina que interactúa con el receptor de insulina fosforilado, es decir, un dominio C-terminal rico en tirosina. Luego de la fosforilación de la tirosina, interactúan con proteínas específicas que contienen el dominio SH2 y que intervienen en la señalización del receptor de insulina.
Concept Schemes:
https://lod.nal.usda.gov/nalt
Términos Genéricos:
proteínas adaptadoras transductoras de señales
Términos Relacionados:
URI:
https://lod.nal.usda.gov/nalt/294108
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RDF/XMLCreated 2017-03-02, last modified 2017-11-10