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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Fields of Study > immunology > immunologic factors > cytokines > chemokines > beta chemokines > monocyte chemoattractant proteins > chemokine CCL13
Research, Technology, Methods > research > animal research > chemical substances > biochemical compounds > amino acids, peptides and proteins > peptides > cytokines > chemokines > beta chemokines > monocyte chemoattractant proteins > chemokine CCL13
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > peptides > cytokines > chemokines > beta chemokines > monocyte chemoattractant proteins > chemokine CCL13
Preferred Term:

quimiocina CCL13

Definition:
La citosina pequeña inducible A13, inducida por la IL-1 y el TNF-alfa y ampliamente expresada y codificada por el gen CCL13 humano (familia de intercrinas beta) y el 98-aa 11-kD (precursor), constituye un factor quimiotáctico secretado de monocitos, linfocitos, basófilos y eosinófilos que da señales mediante los receptores CCR2B y CCR3 e interviene en procesos inmunorreguladores e inflamatorios. La proteína puede enlazar la heparina y las isoformas MCP-4, (LA) MCP-4 y (FNPQGLA) MCP-4. El gen CCL13 puede intervenir en el desarrollo de la aterosclerosis.
Concept Schemes:
https://lod.nal.usda.gov/nalt
Términos Genéricos:
proteínas quimioatrayentes de monocitos
Términos Relacionados:
URI:
https://lod.nal.usda.gov/nalt/243281
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RDF/XMLCreated 2015-03-10, last modified 2015-11-16