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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > chemical compounds > organic compounds > heterocyclic compounds > rifamycins > rifampicin
Research, Technology, Methods > drugs > anti-infective agents > antibiotics > rifamycins > rifampicin
Research, Technology, Methods > chemical substances > chemical compounds > organic compounds > organic nitrogen compounds > amides > lactams > rifamycins > rifampicin
Research, Technology, Methods > chemical substances > chemical compounds > nitrogen compounds > organic nitrogen compounds > amides > lactams > rifamycins > rifampicin
Preferred Term:

rifampicin

Definition:
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms.
Concept Schemes:
NALT Core
NALT Full
Broader Concept:
rifamycins
Entry Terms:
  • rimactan
  • rifampin
  • rifadin
URI:
https://lod.nal.usda.gov/nalt/61571
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2015-06-15
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