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Preferred Term:

nonsense mutation

A mutation in which a sense codon (which codes for an amino acid) is converted to the same sequence as a stop codon. This abnormal occurrence causes premature termination of protein translation resulting in the production of truncated proteins which may be non-functional.
Concept Schemes:
Broader Concept:
Entry Terms:
  • amber mutation
  • opal mutation
  • amber nonsense mutation
  • opal nonsense mutation
  • ochre nonsense mutation
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RDF/XMLCreated 2006-01-19, last modified 2016-03-01