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Preferred Term:

macrophage activation

Definition:
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
Concept Schemes:
NALT Core
NALT Full
Broader Concept:
URI:
https://lod.nal.usda.gov/nalt/46969
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RDF/XMLCreated 2006-01-19, last modified 2013-01-14