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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Fields of Study > genetics > molecular genetics > transcription factors > aryl hydrocarbon receptors
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > transcription factors > aryl hydrocarbon receptors
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > transcription factors > aryl hydrocarbon receptors
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > binding proteins > DNA-binding proteins > orphan nuclear receptors > aryl hydrocarbon receptors
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > binding proteins > DNA-binding proteins > orphan nuclear receptors > aryl hydrocarbon receptors
Preferred Term:

aryl hydrocarbon receptors

Definition:
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Concept Schemes:
NALT Full
Broader Concept:
orphan nuclear receptors, transcription factors
Related Concepts:
Entry Terms:
  • TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) receptors
  • Ah (aryl hydrocarbon) receptors
  • polyaromatic hydrocarbon receptors
  • dioxin receptors
URI:
https://lod.nal.usda.gov/nalt/335856
Download this Concept:
RDF/XMLCreated 2020-02-03, last modified 2020-10-29