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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > toxic substances > toxins > microbial toxins > bacterial toxins > diphtheria toxin
Preferred Term:

diphtheria toxin

Definition:
An ADP-ribosylating polypeptide produced by Corynebacterium diphtheriae that causes the signs and symptoms of diphtheria. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono(ADP-ribose) transferases which transfers ADP ribose to peptide elongation factor 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
Concept Schemes:
NALT Full
Broader Concept:
bacterial toxins
Related Concepts:
URI:
https://lod.nal.usda.gov/nalt/332175
Download this Concept:
RDF/XMLCreated 2019-07-10, last modified 2019-11-25