Preferred Term:
loss of heterozygosity
Definition:
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal hemizygosity. It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted.
Concept Schemes:
NALT Full
Broader Concept:
Narrower Concepts:
Entry Terms:
- allelic loss
URI:
https://lod.nal.usda.gov/nalt/324472
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RDF/XMLCreated 2018-09-18, last modified 2018-11-14