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Preferred Term:

Limulus amebocyte lysate assay

Definition:
Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • Limulus assay
  • Limulus test
URI:
https://lod.nal.usda.gov/nalt/312827
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RDF/XMLCreated 2018-02-01, last modified 2020-04-15