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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > biochemical compounds > growth factors > endothelial growth factors > vascular endothelial growth factors > placental growth factor
Fields of Study > biochemistry > biochemical compounds > growth factors > endothelial growth factors > vascular endothelial growth factors > placental growth factor
Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > animal proteins > pregnancy proteins > placental growth factor
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > animal proteins > pregnancy proteins > placental growth factor
Preferred Term:

placental growth factor

Definition:
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
Concept Schemes:
NALT Full
Broader Concept:
pregnancy proteins, vascular endothelial growth factors
Related Concepts:
URI:
https://lod.nal.usda.gov/nalt/308277
Download this Concept:
RDF/XMLCreated 2017-09-12, last modified 2017-11-22