Preferred Term:
target of rapamycin proteins
Definition:
A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of rapamycin due to the discovery that sirolimus (commonly known as rapamycin) forms an inhibitory complex with tacrolimus binding protein 1A that blocks the action of its enzymatic activity.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- target of rapamycin kinases
- TOR (target of rapamycin) kinases
- rapamycin target proteins
URI:
https://lod.nal.usda.gov/nalt/291499
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RDF/XMLCreated 2017-02-06, last modified 2017-11-10