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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Fields of Study > animal and human health > medical sciences > toxicology > toxicity testing > genotoxicity tests > comet assay
Animals, Livestock, One Health > animal and human health > medical sciences > toxicology > toxicity testing > genotoxicity tests > comet assay
Research, Technology, Methods > methodology > testing > toxicity testing > genotoxicity tests > comet assay
Research, Technology, Methods > methodology > analytical methods > electrophoresis > gel electrophoresis > agar gel electrophoresis > comet assay
Preferred Term:

comet assay

Definition:
A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
Concept Schemes:
NALT Full
Broader Concept:
genotoxicity tests, agar gel electrophoresis
Related Concepts:
Entry Terms:
  • single cell gel electrophoresis assay
  • single-cell gel electrophoresis
URI:
https://lod.nal.usda.gov/nalt/291475
Download this Concept:
RDF/XMLCreated 2017-02-06, last modified 2017-11-10