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Concept Breadcrumbs

Preferred Term:

macrophage colony-stimulating factor

Definition:
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (macrophage colony-stimulating factor receptor).
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • colony stimulating factor 1
  • colony stimulating factor-1
URI:
https://lod.nal.usda.gov/nalt/28007
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2016-05-20