Preferred Term:
cocaine
Definition:
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Concept Schemes:
NALT Full
NALT Core
NALT Core
Broader Concept:
Entry Terms:
- cocaine HCl
- cocaine hydrochloride
URI:
https://lod.nal.usda.gov/nalt/27401
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RDF/XMLCreated 2006-01-19, last modified 2018-07-26