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Preferred Term:

gamma-aminobutyric acid receptors

Definition:
Cell-surface proteins that bind gamma-aminobutyric acid with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • GABA receptors
URI:
https://lod.nal.usda.gov/nalt/271233
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RDF/XMLCreated 2016-01-29, last modified 2017-07-06