Preferred Term:
two hybrid system techniques
Definition:
Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- yeast-two hybrid assay
- two hybrid analysis
- two-hybrid system
- two hybrid assay
- two hybrid screening
URI:
https://lod.nal.usda.gov/nalt/26951
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2017-03-27