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Preferred Term:

two hybrid system techniques

Definition:
Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
  • yeast-two hybrid assay
  • two hybrid analysis
  • two-hybrid system
  • two hybrid assay
  • two hybrid screening
URI:
https://lod.nal.usda.gov/nalt/26951
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RDF/XMLCreated 2006-01-19, last modified 2017-03-27