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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > biochemical compounds > amino acids, peptides and proteins > proteins > neoplasm proteins > tumor suppressor proteins > tumor suppressor protein p53
Fields of Study > biochemistry > biochemical compounds > amino acids, peptides and proteins > proteins > neoplasm proteins > tumor suppressor proteins > tumor suppressor protein p53
Preferred Term:

tumor suppressor protein p53

Definition:
Nuclear phosphoprotein encoded by the p53 gene ( genes, P53) whose normal function is to control cell proliferation and apoptosis. A mutant or absent p53 protein has been found in leukemia; osteosarcoma; lung cancer; and colorectal cancer.
Concept Schemes:
NALT Full
Broader Concept:
tumor suppressor proteins
Related Concepts:
Entry Terms:
  • p53 antigen
  • TRP53 protein
  • oncoprotein p53
URI:
https://lod.nal.usda.gov/nalt/261837
Download this Concept:
RDF/XMLCreated 2015-09-25, last modified 2015-11-30