Preferred Term:
platelet-derived growth factor receptors
Definition:
Specific receptors on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists. The alpha PDGF receptor (receptor, platelet-derived growth factor alpha) and the beta PDGF receptor (receptor, platelet-derived growth factor beta) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
Concept Schemes:
NALT Full
Broader Concept:
Narrower Concepts:
Entry Terms:
- PDGF receptors
URI:
https://lod.nal.usda.gov/nalt/245644
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RDF/XMLCreated 2015-03-26, last modified 2015-11-16