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Concept Breadcrumbs

Preferred Term:

proliferating cell nuclear antigen

Definition:
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
Concept Schemes:
NALT Full
https://lod.nal.usda.gov/nalt-core
Entry Terms:
  • PCNA (proliferating cell nuclear antigen)
URI:
https://lod.nal.usda.gov/nalt/23384
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2017-07-06
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