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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > technical chemicals > chemical inhibitors > metabolic inhibitors > enzyme inhibitors > proteinase inhibitors > angiotensin-converting enzyme inhibitors
Preferred Term:

angiotensin-converting enzyme inhibitors

Definition:
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Concept Schemes:
NALT Full
Broader Concept:
proteinase inhibitors
Related Concepts:
Entry Terms:
  • angiotensin I-converting enzyme inhibitors
  • kininase II inhibitors
  • kininase II antagonists
  • ACE inhibitors
URI:
https://lod.nal.usda.gov/nalt/228984
Download this Concept:
RDF/XMLCreated 2014-09-17, last modified 2020-04-14