Preferred Term:
erbB-3 receptor
Definition:
A cell surface protein-tyrosine kinase receptor that is specific for neuregulins. It has extensive homology to and can heterodimerize with the EGF Receptor (epidermal growth factor receptor) and the erbB-2 receptor. Overexpression of the erbB-3 receptor is associated with tumorigenesis.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- HER-3 proto-oncogene protein
- c-erbB-3 receptor
- HER-3 protein
- proto-oncogene proteins erbB-3
- human epidermal growth factor receptor 3
- c-erbB-3 protein
- proto-oncogene protein c-erbB-3
- HER-3 receptor
URI:
https://lod.nal.usda.gov/nalt/222857
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RDF/XMLCreated 2014-07-25, last modified 2014-11-17