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Preferred Term:

erbB-3 receptor

Definition:
A cell surface protein-tyrosine kinase receptor that is specific for neuregulins. It has extensive homology to and can heterodimerize with the EGF Receptor (epidermal growth factor receptor) and the erbB-2 receptor. Overexpression of the erbB-3 receptor is associated with tumorigenesis.
Concept Schemes:
NALT Full
Entry Terms:
  • HER-3 proto-oncogene protein
  • c-erbB-3 receptor
  • HER-3 protein
  • proto-oncogene proteins erbB-3
  • human epidermal growth factor receptor 3
  • c-erbB-3 protein
  • proto-oncogene protein c-erbB-3
  • HER-3 receptor
URI:
https://lod.nal.usda.gov/nalt/222857
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RDF/XMLCreated 2014-07-25, last modified 2014-11-17