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Preferred Term:

hepatocyte growth factor receptor

Cell surface protein-tyrosine kinase receptors for hepatocyte growth factor. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations of the gene for proto-oncogene proteins c-Met are associated with papillary renal carcinoma and other neoplasia.
Concept Schemes:
Entry Terms:
  • proto-oncogene proteins c-Met
  • proto-oncogene protein c-Met
  • HGF receptor
  • c-Met proteins
  • Met proto-oncogene tyrosine kinase
  • tyrosine-protein kinase Met
  • scatter factor receptor
  • proto-oncogene c-Met
  • HGF/SF receptor
  • receptor tyrosine kinase c-Met
  • c-Met proto-oncogene proteins
  • SF receptor
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RDF/XMLCreated 2014-07-25, last modified 2018-05-25