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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > technical chemicals > chemical inhibitors > metabolic inhibitors > enzyme inhibitors > cholinesterase inhibitors
Preferred Term:

cholinesterase inhibitors

Definition:
Drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Concept Schemes:
NALT Full
Broader Concept:
enzyme inhibitors
Related Concepts:
Entry Terms:
  • anticholinesterase agents
  • acetylcholinesterase inhibitors
  • anticholinesterase drugs
  • anti-cholinesterases
URI:
https://lod.nal.usda.gov/nalt/22191
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2019-12-16
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