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tandem mass spectrometry

A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, gas chromatography-mass spectrometry is involved in separating relatively small compounds by gas chromatography prior to injecting them into an ionization chamber for the mass selection.
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Entry Terms:
  • mass spectrometry-mass spectrometry
  • MS/MS (mass spectrometry-mass spectrometry)
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RDF/XMLCreated 2014-06-26, last modified 2019-02-01