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Preferred Term:

PrPC proteins

Definition:
Normal cellular isoform of prion proteins (prions) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
Concept Schemes:
NALT Full
Broader Concept:
URI:
https://lod.nal.usda.gov/nalt/217658
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RDF/XMLCreated 2014-06-04, last modified 2014-11-17