Preferred Term:
antibody affinity
Definition:
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- antibody avidity
URI:
https://lod.nal.usda.gov/nalt/217636
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RDF/XMLCreated 2014-06-04, last modified 2017-04-12