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macrophage-1 antigen

An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b antigen and the beta subunit the CD18 antigen. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Concept Schemes:
Broader Concept:
Entry Terms:
  • Mac-1 receptor
  • integrin alphaMbeta2
  • CR3 integrin
  • CR3 receptor
  • Mac-1 antigen
  • adhesive receptor Mac-1
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RDF/XMLCreated 2014-02-28, last modified 2014-11-17