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Research, Technology, Methods > chemical substances > biochemical compounds > enzymes > transferases > phosphotransferases (kinases) > protein kinases > protein-tyrosine kinases > receptor protein-tyrosine kinase > vascular endothelial growth factor receptors > vascular endothelial growth factor receptor-1
Fields of Study > biochemistry > biochemical compounds > enzymes > transferases > phosphotransferases (kinases) > protein kinases > protein-tyrosine kinases > receptor protein-tyrosine kinase > vascular endothelial growth factor receptors > vascular endothelial growth factor receptor-1
Preferred Term:

vascular endothelial growth factor receptor-1

Definition:
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Concept Schemes:
NALT Full
Broader Concept:
vascular endothelial growth factor receptors
Entry Terms:
  • VEGFR-1
  • VEGF receptor flt
  • proto-oncogene protein flt
  • flt1 receptor tyrosine kinase
  • VEGF receptor flt-1 protein
URI:
https://lod.nal.usda.gov/nalt/208111
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RDF/XMLCreated 2013-11-15, last modified 2015-04-21