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The segregation and degradation of various cytoplasmic constituents via engulfment by multivesicular bodies; vacuoles; or autophagosomes and their digestion by lysosomes. It plays an important role in biological metamorphosis and in the removal of bone by osteoclasts. Defective autophagy is associated with various diseases, including neurodegenerative diseases and cancer.
Concept Schemes:
Broader Concept:
Entry Terms:
  • autophagic programmed cell death
  • autophagic cell death
  • type 2 programmed cell death
  • autophagocytosis
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RDF/XMLCreated 2013-09-24, last modified 2020-04-14