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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Fields of Study > animal and human health > diseases and disorders (animals and humans) > animal diseases > cattle diseases > bovine leukocyte adhesion deficiency
Animals, Livestock, One Health > animal and human health > diseases and disorders (animals and humans) > animal diseases > cattle diseases > bovine leukocyte adhesion deficiency
Fields of Study > animal and human health > diseases and disorders (animals and humans) > noninfectious diseases > genetic disorders > bovine leukocyte adhesion deficiency
Animals, Livestock, One Health > animal and human health > diseases and disorders (animals and humans) > noninfectious diseases > genetic disorders > bovine leukocyte adhesion deficiency
Fields of Study > animal and human health > diseases and disorders (animals and humans) > hematologic diseases > leukocyte disorders > bovine leukocyte adhesion deficiency
Animals, Livestock, One Health > animal and human health > diseases and disorders (animals and humans) > hematologic diseases > leukocyte disorders > bovine leukocyte adhesion deficiency
Preferred Term:

bovine leukocyte adhesion deficiency

Definition:
An autosomal recessive hereditary disease affecting young Holstein calves. Homozygous individuals die from extreme susceptibility to infection, caused by an inability of leukocytes to pass from the blood stream into infected tissue. This inability is due to the lack of beta-2 integrin adhesion protein on the surface of the white blood cells due to two point mutations in the CD18 gene.
Concept Schemes:
NALT Full
Broader Concept:
cattle diseases, leukocyte disorders, genetic disorders
Entry Terms:
  • BLAD (animal disease)
URI:
https://lod.nal.usda.gov/nalt/17877
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2012-11-30