Preferred Term:
interferon-alpha
Definition:
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates natural killer cells and B-lymphocytes, and down-regulates vascular endothelial growth factor expression through PI-3 kinase and MAPK kinases signaling pathways.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- alpha interferon
- alpha-interferon
- interferon alpha-A
URI:
https://lod.nal.usda.gov/nalt/143748
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RDF/XMLCreated 2011-03-30, last modified 2020-03-02