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NAL Agricultural Thesaurus
U.S. Department of Agriculture

Concept Breadcrumbs

Research, Technology, Methods > chemical substances > biochemical compounds > growth factors > fibroblast growth factors > fibroblast growth factor 1
Fields of Study > biochemistry > biochemical compounds > growth factors > fibroblast growth factors > fibroblast growth factor 1
Preferred Term:

fibroblast growth factor 1

Definition:
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. It binds to heparin, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (fibroblast growth factor 2).
Concept Schemes:
NALT Full
Broader Concept:
fibroblast growth factors
Entry Terms:
  • acidic fibroblast growth factor
  • fibroblast growth factor, acidic
  • fibroblast growth factor-1
URI:
https://lod.nal.usda.gov/nalt/126905
Download this Concept:
RDF/XMLCreated 2006-01-19, last modified 2015-01-15