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inhibitory concentration 50

The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
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Broader Concept:
Entry Terms:
  • 50% inhibitory concentration
  • IC50
  • IC-50
  • IC 50
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RDF/XMLCreated 2006-10-23, last modified 2017-10-11
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