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Preferred Term:

inhibitory concentration 50

Definition:
The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
Concept Schemes:
https://lod.nal.usda.gov/nalt-awic
NALT Core
https://lod.nal.usda.gov/nalt
Broader Concept:
Entry Terms:
  • 50% inhibitory concentration
  • IC50
  • IC-50
  • IC 50
URI:
https://lod.nal.usda.gov/nalt/68543
Download this Concept:
RDF/XMLCreated 2006-10-23, last modified 2017-10-11
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