Preferred Term:
rifampicin
Definition:
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms.
Concept Schemes:
NALT Core
Broader Concept:
Entry Terms:
- rimactan
- rifampin
- rifadin
URI:
https://lod.nal.usda.gov/nalt/61571
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RDF/XMLCreated 2006-01-19, last modified 2015-06-15
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