A gene silencing phenomenon whereby specific dsRNAs (RNA, double-stranded) trigger the degradation of homologous mRNA (RNA, messenger). The specific dsRNAs are processed into small interfering RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-induced silencing complex. DNA methylation may also be triggered during this process.
- posttranscriptional gene silencing
- RNA silencing
- RNAi (RNA interference)
- RNA interference (RNAi)
- post-transcriptional gene silencing
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RDF/XMLCreated 2006-01-19, last modified 2016-03-22