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Preferred Term:

lymphocyte proliferation

Morphologic alteration of small B lymphocytes or T lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by interleukins, mitogens such as phytohemagglutinins, and by specific antigens. It may also occur in vivo, as in graft rejection.
Concept Schemes:
Broader Concept:
Entry Terms:
  • lymphocyte stimulation
  • lymphoblast transformation
  • blast transformation
  • lymphocyte activation
  • lymphocyte transformation
  • blastogenesis
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RDF/XMLCreated 2006-01-19, last modified 2017-07-06