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proteasome endopeptidase complex

A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
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Entry Terms:
  • proteasome complex
  • EC
  • proteasome
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RDF/XMLCreated 2008-10-24, last modified 2017-05-02
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